A Fast Quantitative Mass Spectrometric Analysis for 1,25-dihydroxyvitamin D3
- 詳細技術說明
- A new technique has been developed for the accurate measurement of1,25-dihydroxyvitamin D3 (1,25(OH)2D3) using mass spectrometry. Theassay is specific for 1,25(OH)2D3, and it can be performed in a matterof minutes with simple sample preparation protocols. Vitamin D3 iscritical to many physiological processes, and 1,25(OH)2D3 is its activemetabolite. A 1,25(OH)2D¬3 deficiency can lead to organ and bonedisorders, while excess 1,25(OH)2D3 is associated with digestivedisorders and ischemic heart disease. Therefore, measurement of1,25(OH)2D3 is an emerging tool in preventative medicine. Existingdiagnostics are plagued by inaccurate and irreproducible results, andthis new diagnostic technology can potentially overcome these issues.
- *Abstract
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- *Publications
- No references or resources available.
- *Stage of Development
- Proof of concept studies have been completed for the measurement of1,25(OH)2D3. Quantitative assays and kits are being developed, andGeorgetown is seeking a partner for further development andcommercialization.
- 國家/地區
- 美國

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