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Novel Cannabinergic Nitrate Esters and Related Analogs

技术优势

The cannabinergic nitrate esters:ΓÇóExhibit a dual functional behaviorΓÇóAre good nitric oxide donorsΓÇóHave improved physiochemical propertiesΓÇóAre capable of covalently binding to receptors in a unique mannerΓÇóHave a predictable onset and duration of action as compared to conventional compoundsΓÇóPossess exceptional and distinct in-vivo and in-vitro pharmacological propertiesΓÇóAre capable of acting as agonists, partial agonists, neutral antagonists or inverse agonists for various receptors

详细技术说明

None

*Abstract

In prior art, various attempts have been made to explore and understand the medicinal effects of marijuana unrelated to its psychoactive properties. As a result, various cannabinoidal compounds have been identified and experimented till date. However, identification of cannabinoidal compounds with nitrate ester groups have never been reported or studied. This approach discloses development and use of such novel compounds for various therapeutic/research applications.

*Principal Investigation

Name: Venkata Kiran Vemuri

Department:

Name: Alexandros Makriyannis

Department:

国家/地区

美国