Semapimod inhibits the expression of the proapoptotic and proinflammatory proteins HMGB1, Bad, Bax and COX-2
- 详细技术说明
- None
- *Abstract
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The inventors have found that daily administration of semapimod decreases the protein expression of HMGB1, Bad, Bax and COX-2 in the intestines of formula-fed newborn rats exposed to hypoxia and protects against chronic intestinal injury in an animal model of necrotizing enterocolitis (NEC).Non Provisional Patent Application Filed
- *Principal Investigation
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Name: Henri Ford
Department: Med-Surgery
Name: Ruben Zamora, Assistant Professor of SurgeryAssistan
Department: Med-Surgery
- 国家/地区
- 美国
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