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Semapimod inhibits the expression of the proapoptotic and proinflammatory proteins HMGB1, Bad, Bax and COX-2

Detailed Technology Description
None
*Abstract
The inventors have found that daily administration of semapimod decreases the protein expression of HMGB1, Bad, Bax and COX-2 in the intestines of formula-fed newborn rats exposed to hypoxia and protects against chronic intestinal injury in an animal model of necrotizing enterocolitis (NEC).Non Provisional Patent Application Filed
*Principal Investigator

Name: Henri Ford

Department: Med-Surgery


Name: Ruben Zamora, Assistant Professor of SurgeryAssistan

Department: Med-Surgery
Country/Region
USA

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