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Bioreactor System For The Large Scale Production Of Pluripotent Stem Cells And Their Derivatives. (Hadasit)

总结

There is a great need for the development of a robust large scale cell production to facilitate the development of novel hPSC based therapeutics.  The exploitation of Human pluripotent stem cells (hPSCs) for regenerative medicine and stem cell based R&D applications will depend on the availability of a large scale production or “banking” platform for hPSCs and their differentiated progeny.  The lack of hPSC large scale production platforms presents a serious challenge for successful translation of novel cell based therapies into clinical settings.  There is a great need for the development of a robust large scale cell production to facilitate the development of novel hPSC based therapeutics.  We are currently developing a bioreactor system for large scale production of hPSCs.  Our investigators are aiming at providing a proof of concept for the feasibility of an automated dynamic bioreactor culture system.

技术优势

Currently, hPSCs are propagated as monolayer colonies within highly variable and labor-intensive culture systems, which do not allow large-scale production of standardized homogenous hPSCs.

技术应用

Novel hPSC based therapeutics.

ID号码

8-2010-83

国家/地区

以色列