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Medicinal plant compound reduces mycotoxins and sporulation

Detailed Technology Description
Executive Summary Economic losses due to mycotoxins in the United States are estimated to be between $0.5 and $1.5 billion annually. Fungicides are only partially effective against mycotoxin-producing fungi because such fungi are naturally tolerant to many fungicides, and because when stressed by fungicide applications, fungi can respond by producing more of the mycotoxin. Durable host plant resistance is not available, despite many years of intensive breeding. An alternative to these solutions would be a compound or compounds that block mycotoxin biosynthesis, especially when mycotoxin levels can be high, even in asymptomatic nuts and grains. A medicinal plant extract shows promise in safely replacing synthetic pesticides for prevention of aflatoxin contamination in stored grains and nuts Diospyros species root powder, root powder extracts, and purified DQ and 3-HDQ compounds all effectively inhibit aflatoxin production. DQ and 3-HDQ also block spore formation by Aspergillus. Description Technology This technology is compositions useful for blocking mycotoxin production and spore production by fungi that contaminate grains and nuts, thereby stabilizing the quality of stored grains and nuts.  This reduces post-harvest losses due to mycotoxin contamination.  The compositions may also be used to treat crop plants pre-harvest.  Compositions include Diospyros root powder, root powder extracts, and the active compounds DQ and 3-HDQ.  Key BenefitsReduces aflatoxin accumulationNatural productsReadily availableInexpensive ApplicationsFood crops:  storage or pre-harvest applicationAnimal feed: storage or pre-harvest application Patent Status:  Patent pending Licensing Rights Available Full licensing rights available Inventors: Gale M. Strasburg, Juma A. Mmongoyo, John E. Linz, Felicia Wu, Jovin K. Mugula Amila A. Dissanayake, Chuan-Rui Zhang, Josephine M. Wee, Muraleedharan G. Nair  Tech ID: 2017-0033
*Abstract
None
*Principal Investigator

Name: Gale Strasburg, Professor and Chairperson

Department: Food Science & Human Nutrition


Name: John Linz, Professor

Department: Food Science & Human Nutrition


Name: Felicia Wu, Hannah Distinguished Professr

Department: Department of Food Science & Human Nutrition


Name: Muraleedharan Nair, Professor

Department: Department of Horticulture


Name: Juma Mmongoyo, Graduate Student

Department: Food Science and Human Nutrition


Name: Jovin Mugula, Associate Professor

Department: Department of Food Technology, Nutrition and Consumer Sciiences


Name: Amila Dissanayake, Research Associate

Department: Horticulture


Name: Chuan-rui Zhang

Department: Horticulture


Name: Josephine Wee, Research Associate

Department: Food Science and Human Nutrition


Name: Devin Day

Department:

Country/Region
USA

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