Development of Laser-Induced Cell Lysis System
- Detailed Technology Description
- This laser induced cell lysis system is effective in lysing bacteria for the purpose of bioanalytically detection of bacterial pathogens in food, water, environmental samples or on medical devices and supplies
- Others
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None
- *Abstract
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This laser induced cell lysis system is effective in lysing bacteria for the purpose of bioanalytically detection of bacterial pathogens in food, water, environmental samples or on medical devices and supplies. The lasers destroy the cell membrane without damaging the interior of the cell thus exposing the proteins and nucleic acids for detection. Other methods rely on mechanical, physical or chemical manipulation to lyse cells in order to expose intracellular proteins, DNA, or RNA for detection purposes. Unlike this cell laser method, these methods are labor intensive, time requiring and can damage or alter the very molecule you are trying to detect.
Potential Applications:
This device can be combined with other systems/devices to lyse cells for applications in:
- testing pathogens in the water supply
- examining contaminants in other liquids
- testing pathogens in biological samples
- determining levels of any organism as a clinical diagnostic
- determining certain nucleic acid sequences for research purposes
Advantages:
- Rapid, non-damaging method to lyse cells
- No adverse chemicals introduced to system
- Simple to execute and adapt to multiple applications for use
- *Licensing
- Jeff Fearn, Senior Technology Commercialization and Liaison Officerjcf55@cornell.edu607-254-4502
- Country/Region
- USA
