NIR-Induced Payload Release from Polymeric Carriers and Applications Thereof
- Detailed Technology Description
- University researchers have developed a technique based on a simple mechanism that provides a highly universal strategy enabling instantaneous and controlled release of material from non-light-sensitive polymer carriers using low-power pulsed or continuous-wave NIR. Applications include light-activated self-healing capsules, extracellular scaffolds (nano-fibers, hydrogels) capable of providing on-demand delivery of cues for cell proliferation, differentiation, or migration, activatable fluorescent particles based on thermo-chromic dyes, and light-triggered drug delivery systems.
- Application No.
- 9700620
- Others
-
Tech ID/UC Case
23412/2013-037-0
Related Cases
2013-037-0
- *Abstract
-
Light-triggered release from polymeric carriers enables precise spatial and temporal control; carriers responsive to near-infrared (NIR) light are particularly relevant for biomedical applications, as tissue absorption and scattering of light are considerably lower in the NIR window. Existing mechanisms for NIR-triggered release are limited in their application, requiring custom synthesis of designer polymers, high powered lasers to drive inefficient two-photon processes and/or co-encapsulation of bulky inorganic particles.
- *IP Issue Date
- Jul 11, 2017
- *Principal Investigator
-
Name: Mathieu Lessard-Viger
Department:
Name: Adah Almutairi
Department:
Name: Wangzhong Sheng
Department:
- Country/Region
- USA
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