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DNA-based high spatial resolution thermometer based on temperature dependent fluorescence

Summary
Kenneth Shepard, Ph.D.
Technology Benefits
Can measure temperature in systems that are incompatible with contemporary thermometersThe temperature range can be altered by synthetically changing the DNAHighly customizable temperature probeInexpensive componentsResolution not limited by the thermometer, but by the optics used to image the sample. The resolution will improve with improved optics.Patent information:Patent Pending (US 20130224879)Tech Ventures Reference: IR M11-123
Technology Application
Sample temperature measurements, in vivo and in vitroLaboratory experiments that require high spatial resolution temperature measurements, such as MEMS or lab-on-a-chip applicationsBiological temperature sensorTemperature profile measurements of integrated circuits, cells, and MEMS structures
Detailed Technology Description
Kenneth Shepard, Ph.D.
*Abstract
None
*Inquiry
Jay HickeyColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
M11-123
*Principal Investigator
*Publications
Norian, H., Field, R.M., Kymissis, I., Shepard, K.L. "An integrated CMOS quantitative-polymerase-chain-reaction lab-on-chip for point-of-care diagnostics." Lab on a Chip, 2014. 14, 4076-4084.
Country/Region
USA

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