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Targeted drug delivery with focused ultrasound induced blood-brain barrier opening

Summary: Elisa Konofagu, Ph.D..

Technology Benefits: Targeted delivery of therapeutic agents across the blood brain barrierFacilitates focused ultrasound induced blood brain barrier opening using an extravascular agentCan facilitate higher injection doses with reduced side effectsPatent information:Patent Pending Tech Ventures Reference: IR CU14035

Technology Application: Therapeutic preferential permeation of tissues such as the blood brain barrierTargeted drug delivery through the blood brain barrierDelivery of contrast agent to the extravascular space for imaging and therapeutic applicationsDrug delivery for Alzheimer's diseaseDrug delivery for Parkinson's disease

Detailed Technology Description: Elisa Konofagu, Ph.D..

*Abstract: None

*Inquiry: Satish RaoColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: CU14035

*Principal Investigator

*Publications: Chen C, Sheeran P, Wu S, Olumolade O, Dayton P, Konofagou E. "Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets", Journal of Controlled Release. 2013 Dec;172(3):795-804.

Country/Region: USA

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