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Identification of causal genetic mutations for the early diagnosis of Parkinson's Disease

Summary: Asa Abeliovich, M.D., Ph.D.

Technology Benefits: Identifies causal factors of Parkinson's Disease and provides a potential biomarker for the diagnosis of disease as well as therapeutic approaches.Employs a methodology that can serve as a platform for the study of multiple other diseases, including other neurodegenerative disorders.Patent information:Patent Pending (WO/2013/086041)Tech Ventures Reference: IR 2837

Technology Application: Identifies genetic biomarkers that could aid in the diagnosis of Parkinson's Disease.Potential application as a pathological identifier in other diseases that result from transcription errors or neural degeneration.

Detailed Technology Description: Asa Abeliovich, M.D., Ph.D.

*Abstract: None

*Inquiry: Jerry KokoshkaColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: 2837

*Principal Investigator

*Publications: H. Rhinn, L. Qiang, T. Yamashita, D. Rhee, Z. Zolin, W. Vanti, A. Abeliovich. Alternative a-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology. Nature Communications, Vol. 3, 2012, 1084.

Country/Region: USA

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