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Development of Anti-angiogenic miRNA Therapeutics for Corneal Neovascularization

Detailed Technology Description: This new technology includes two novel inventions: 1) discovery of miRNAs that influence the neovascularization of the cornea and 2) optimization of rAAV gene therapy method for specific delivery to t

Countries: Not Available

Application No.: None

*Abstract: This new technology includes two novel inventions: 1) discovery of miRNAs that influence the neovascularization of the cornea and 2) optimization of rAAV gene therapy method for specific delivery to the cornea. Neovascularization is the most common corneal pathological condition and underestimated cause of blindness. Injection of the rAAV constructs that include synthetic nucleic acids that mimic or inhibit the discovered miRNA can reduce corneal neovascularization in mice.

*IP Issue Date: None

*IP Type: Other Patent

Country/Region: USA

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