Preparation of Super-Stable Gold Nanorods via Encapsulation into Block Copolymer Micelles
- Summary
- To address this, researchers at Purdue University have developed a self-assembly process that encapsulates GNRs into block copolymer micelles. The resultant GNRs are stable against aggregation, even under physiological salt conditions, for indefinite periods of time. This method can be scaled up for mass production and can easily be extended to encapsulate and stabilize other nanoparticle agents.
- Technology Benefits
- Stable for indefinite periods of timeCan be scaled for mass production Encapsulate and stabilize other nanoparticle agents
- Technology Application
- PharmaceuticalsMedical/Healthcare
- Detailed Technology Description
- You-Yeon WonPurdue Chemical Engineering
- Countries
- United States
- Application No.
- None
- *Abstract
-
- *Background
- Gold nanorods (GNR) have potential uses as imaging agents or in cancer treatments because of their ability to be tuned to absorb or scatter various types of light. Gold particles could be injected into the body near a tumor and then heated with a light source to selectively kill the cancer cells. Unfortunately, current fabrication techniques create GNRs that are cytotoxic and breakdown quickly in a saline solution.
- *IP Issue Date
- None
- *IP Type
- Provisional
- *Stage of Development
- Proof of Concept
- *Web Links
- Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipYou-Yeon WonPurdue Chemical Engineering
- Country/Region
- USA

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