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Microfluid Platform to Screen Cancer Drug for Delivery

Summary
Researchers at Purdue University have developed a microfluidic platform to simulate a 3D tumor vasculature system. This innovative platform can mimic the complex transport processes inside a tumor, such as transvascular transport, interstitial transport, and transmembrane transport. These processes are all simulated on a single benchtop device, thus improving the repeatability and speed of testing, while reducing the cost and use of animals in drug discovery.
Technology Benefits
Mimics multiple transport processesIncreased repeatability and speed for drug testing Low cost
Technology Application
Medical/HealthPharmaceutical industry Drug developmentResearch labs
Detailed Technology Description
Kinam ParkPurdue Biomedical EngineeringPurdue Industrial and Physical Pharmacy
Countries
United States
Application No.
9,081,003
*Abstract

*Background
Developing and testing cancer drugs is an expensive process that requires, among other things, exhaustive in vivo animal experiments. One aim of preclinical animal studies is to analyze how effectively a drug is transported and delivered to its target in a tumor mass. However, animal testing can be an expensive and slow process.
*IP Issue Date
Jul 14, 2015
*IP Type
Utility
*Stage of Development
Concept Developed
*Web Links
Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipKinam ParkPurdue Biomedical EngineeringPurdue Industrial and Physical Pharmacy
Country/Region
USA

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