Biofunctional Membrane for Detection of Pharmaceuticals and Toxins
- Summary
- Researchers at Purdue University have developed novel approaches that allow the active transport structures on the biofunctional membranes to be oriented in large arrays and supported to provide directional transport and mechanical stability. This has been achieved using synthetic chemical and biological materials that are known to enhance stability. This approach will facilitate identification of promising pharmaceutical compounds, fingerprinting unknown environmental toxins based on membrane protein activity patterns, and rapid, high-throughput analysis of drug candidates for human multidrug resistance transporters and other membrane protein targets of disease.
- Technology Benefits
- AutomatedUses smaller quantities FasterStructure arrangement provides membrane with mechanical stabilityFacilitates identification of pharmaceutical compounds
- Technology Application
- Medical/HealthcarePharmaceuticalsDrug DeliveryBiotechnology
- Detailed Technology Description
- David ThompsonThompson GroupPurdue ChemistryPurdue Biomedical Engineering
- Countries
- United States
- Application No.
- 7,374,944
- *Abstract
-
- *Background
- Biofunctional asymmetric membranes allow unidirectional transport of chemical and biological agents.
- *IP Issue Date
- May 20, 2008
- *IP Type
- Utility
- *Stage of Development
- Process Validation in Lab
- *Web Links
- Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipDavid ThompsonThompson GroupPurdue ChemistryPurdue Biomedical Engineering
- Country/Region
- USA
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