Epitope Delivery for Effective Anti-Tumor Immunotherapy
- Detailed Technology Description
- Executive Summary MSU researchers have discovered a way to activate our natural immune system to lead the fight against cancer. By activating the innate immune system which does not normally recognize cancer, the severe side effects common to cancer therapeutics can be significantly reduced or avoided altogether. This research has the potential to change the paradigm on how we treat cancer. Description of Technology The therapeutic efficacy of current technology can be improved by this MSU discovery due to the enhanced epitope cross-presentation. This epitope cross-presentation, in effect labels the cancer for destruction by the immune system via increased cytotoxic T-cell attack. This technique leads to a 100% survival rate in a 30-day mouse model, whereas untreated mice were deceased after 20 days. Key BenefitsDecreased tumor growth rate for a broad range of different tumor cells. ApplicationsTumor / Cancer Therapy / Immunotherapy Patent Status: Under review Licensing Rights Available Full licensing rights available Inventors: Dr. Xuefei Huang, Herbert Kavunja, Shuyao Lang, Suttipun Sungsuwan, Dr. Zhaojun Yin Tech ID: TEC2016-0096 Alternative contact due to temporary leave: Nina (Isi) Davis, Technology Marketing Manager, email: davisnin@msu.edu, phone (direct): (517)884-1829.
- *Abstract
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- *Principal Investigator
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Name: Xuefei Huang, Professor
Department: Chemistry
Name: Herbert Kavunja, Graduate Student
Department:
Name: Shuyao Lang, Doctoral Student
Department: Chemistry
Name: Suttipun Sungsuwan, Student
Department: Chemistry
Name: Zhaojun Yin, Visiting Research Associate
Department: Chemistry
- Country/Region
- USA
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