Innovative Methods for Multi-Modality Image Adaptive Radiotherapy & Replanning
- Reduced risk of excess radiation to surrounding healthy tissues- Increase in the amount of radiation delivered to the target tissue- Determination of dose gradients from dose distribution in original plan for all critical structures near the target: replanning optimization runs to maintain the originally planned dose gradients (unlike regular optimization methods that rely on dose-volume criteria which vary drastically from day to day due to the variation in the volume of organs like the rectum and bladder)- Enables automated delineation based on MRI or CT- Allows use of only MRI for radiation treatment planning & drastically reduces replanning time- On-line correction (unlike off-line) strategies correct for both systematic and random variations- On-line correction (unlike off-line corrections) apply to a therapy course with a small number of treatment fractions, such as hypo-fractionation or stereotactic body RT (SBRT)- Generation of the daily OAR is not required with Gradient maintenance (GM) & makes daily re-planning more reproducible & eliminates necessity for trial & error effort
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USA
