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New Agar Medium for the Isolation and Testing Susceptibility of Mycobacterium Tuberculosis Against Drugs

Technology Benefits
The medium can be used in regular incubators (without supplemental CO2)The medium can be used at pH 6.0The medium can be used for a test with pyrazinamidThe medium is using animal serum (bovine serum for example) instead of OADCThe medium is less expensive to producePyrazinamide test can be performed more easily and faster
Technology Application
Isolation of M tuberculosis from patients specimensSub-cultivation of M. tuberculosis pure culturesDirect and indirect susceptibility testing.
Detailed Technology Description
The medium has been successfully tested to isolate M. tuberculosis and for susceptibility with pyrazinamide
Supplementary Information
Inventor: Heifets, Leonid | Sanchez, Tracy
Priority Number: US6579694B2
IPC Current: C12N000120 | C12Q000104 | C12Q000118
US Class: 435034 | 435391 | 435431
Assignee Applicant: National Jewish Medical and Research Centernver
Title: Agar medium for the growth of Mycobacterium tuberculosis
Usefulness: Agar medium for the growth of Mycobacterium tuberculosis
Summary: For culturing Mycobacterium tuberculosis and for testing the drug susceptibility of the culture (claimed). For susceptibility/resistance screening of the culture against a wide range of the drug.
Novelty: New medium useful for the growth of specified bacteria contains an agar base and an animal serum
Industry
Biomedical
Sub Category
DNA/Gene Engineering
*Abstract
Scientists at National Jewish Health have developed a new agar medium for the isolation of M. tuberculosis from patients. The medium can also be used for testing susceptibility of M. tuberculosis against various drugs such as pyrazinamide.
*Principal Investigator

Name: Leonid Heifets, Director

Department: Department of Medicine

Country/Region
USA

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