Described are nucleic acid aptamers that are able to bind to and inhibit the function of sclerostin, which is an important negative regulator of bone growth. The aptamers have application as therapeutics for diseases of bone including osteoporosis, osteopenia, osteoarthritis and other osteoporosis-r.....
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Large scale multicast of video and audio materials over IP networks is becoming increasingly popular and common. These services are bandwidth intensive and normally require stringent QoS requirements. Also with millions of heterogeneous participants involved, it is a tough problem to organize the ne.....
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For designers in industries whose products are fabricated from planar pieces of sheet material (e.g., metal in ship industry, fabric in apparel industry and toy industry, and leather in shoe industry and furniture industry), how to determine the shape of 2D pieces from designed 3D surface patches no.....
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