• Systemic administration• Visualization in real time at the surgical field• Modular: so other dyes or molecules could be attached to targeting agent• Specific accumulation in the axonal tract of neural tissue• Potentially adaptable to delivery of neurotrophic factors to aid in repair and regenerati.....
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Researchers at UCSD have developed a method to deliver siRNA into cells by reversibly masking or neutralizing the charge on the dsRNA using a fusion protein of the TAT delivery peptide and the dsRNA binding domains (DRBDs). The DRBDs, four DRBDs cover the surface of the dsRNA cylinder, bind specifi.....
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This invention is an intelligent medical tweezers that can measure tissue stiffnessand thickness, and transmit the data using built-in RF channels, enabling surgeons to make more informed suturing choices during surgery.
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Applications Contains the empty sgRNA backbone sequence (tracrRNA, 82 bp)and is used as DNA template to amplify a specific sgRNA using a forward primerwith the protospacer sequence for gene targeting. Trypanosoma cruzi CRISPR/Cas9 System plasmids allow for theamplification of a specific sgRNA sequen.....
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