The algorithm:ΓÇóIs parameter freeΓÇóStarts with known disease proteins to finally identify disease neighborhood (s) within the networkΓÇóUses a topology of cellular protein interaction networks to rank all the proteins according to their relevance to the diseaseΓÇóIdentifies a local neighbor.....
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To purify all divergent AAV variants, buoyant density gradients such as CsCl, or iso-osmotic medium iodixanol discontinuous gradients are routinely used. Although quite useful in a laboratory setting, these procedures are neither scalable nor easily adapted for Good Manufacturing Practice (GMP) prot.....
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