For a drug to eliminate HIV-infected cells, a major challenge is to achieve high specificity toward target cells but low cytotoxicity toward normal cells. Maize ribosome-inactivating protein (RIP) contains a 25-amino acid internal inactivation region. Removal of this region generates the active cy.....
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The invention relates to compounds and catalytic reactions to the production of 1,1-disubstituted alkenes or joining the two alkenes at their 2-position, starting from 2 equivalents of the aromatic alkenes (homodimerization) or two different alkenes (heterodimerization) over the production of typica.....
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Cataract is a leading cause of blindness in elderly and diabetic patients. Poor glycemic control can lead to increased conversion of glucose to sorbital via the aldose reductase pathway. Increased accumulation of sorbital has been implicated in the development of cataract. Our group has found an .....
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