The present invention relates to new methods for diagnosing a pregnancy-associated disorder by analyzing fetal DNA present in the mother’s blood. More specifically, this invention relies on the discovery that the maspin gene is differentially methylated in fetal DNA and in maternal DNA and provides.....
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Ankle sprain injury is the most common single type of sport injury. In studying ankle sprain motion, trap-door and inversion platforms were commonly used. However, these devices introduce a rather pure inversion at the ankle joint. In fact, most ankle sprain injuries compromise of a combination o.....
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Cataract is a leading cause of blindness in elderly and diabetic patients. Poor glycemic control can lead to increased conversion of glucose to sorbital via the aldose reductase pathway. Increased accumulation of sorbital has been implicated in the development of cataract. Our group has found an .....
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A method of providing reliable user access to secured files in verification systems is disclosed. In this preferred embodiment, a biometric comparison algorithm is utilized to permit authorized users to access the verification system. A user provides the biometric information, and the involved bio-.....
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The non-invasive detection of fetal chromosomal aneuploidies is demonstrated. Alleles of fetal RNA-SNPs present in a biological sample (e.g. maternal blood) containing fetal RNA are detected and quantified in order to determine the ratio of the alleles. This ratio is compared to a standard control.....
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