This invention allows for the treatment of eosinophilic disorders by administration of an adeno-associated virus (AAV) expressing the genetic sequence for an anti-eosinophil monoclonal antibody.
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Preserves the exquisite specificity of the Ames testQuantitative readout dramatically decreases the amount of sample and of reagents necessary to carry out the testSignificant cost-savings for compounds in early stages of development
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Lead Inventors: Dr. Wei Gu, Ph.D.; Dr. Muyang LiProblem or Unmet Need:p53 is a powerful tumor suppressor protein impaired in over 50% of human cancers. It turns over quickly in cells, degraded primarily by Mdm2-mediated ubiquitination and subsequent proteolysis. Two therapeutic strategies for target.....
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Researchers at Purdue University have developed a new technology that is a catheter-based intravascular imaging in the presence of luminal blood. This technology allows doctors or preclinical researchers to get information about lipid deposit in arterial wall in vivo. It does this by accurately an.....
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