PROTAC technology is emerging as a novel therapeutic method to target diseases caused by the abnormal expression of a disease-causing proteins. PROTACs simultaneously bind a target protein and its E3-ubiquitin ligase, causing ubiquitination and degradation of the target protein. Studying protein-pro.....
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The methods/compositions:ΓÇóEnable differentiation of stem/progenitor cells into oocytes and/or eggsΓÇóCan be applied both ex vivo or in vivo or as a combination to maximize desired outcomesΓÇóProvide a non-invasive procedure to increase oocyte numbers in the ovariesΓÇóAvoid use of potentially harmf.....
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This new system leads to optimal or near-optimal designs with greatly simplified routing architecture. Compared with other methods, it offers: Improved circuit performance due to automatic optimal wire width planning; Better control of performance and area trade-off given the method's flexibility i.....
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Project ID: D2011-33IP Status: Patent Pending U.S and EuropeInvention Description: Novel method to prepare an implantable article comprised of a biocompatible substrate (polymeric or ceramic) to accept a very thin biocompatible, bioactive coating material to facilitate bio-ingrowth between the subst.....
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Lead Inventors: Ed Xuekui WuA method of inducing tag lines in an MRI image which allows adjustment of tag line width and spacing is described. This method uses magnetic resonance imaging by spatial modulation of magnetization to establish a frame of reference in the form of tag lines on the resultin.....
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