RNAi responses have great potential to treat human disease, especially cancer and viral infections. However, siRNAs are macromolecules with no bioavailability to enter cells and require a delivery agent. Here we developed RNAi-molecules delivered into cells by the TAT Peptide Transduction Domain (.....
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The generation of human induced Pluripotent Stem (iPS) cells holds great promise for development of stem cell therapies to treat a wide range of human diseases. However, the generation of iPS cells in the absence of integrative DNA vectors remains problematic. UCSD researchers have developed a si.....
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This discovery may be used to: Develop a simple blood test to screen Lym-1 reactivity of prospective lymphoma patients for Lym-1 treatment, replacing any need for a biopsy. Develop new antibodies that could be used in either diagnostic assays or therapeutic applications for non-Hodgkin's lymphoma.
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• Diagnostic imaging in stroke, carotid occlusion, and cerebral ischemia • Image based guidance for intra-arterial treatment of stroke • Risk assessment for stroke • Evaluation of blood supply to tumors • Evaluation of blood supply to organ transplants such as kidneys • Evaluation of collateral bloo.....
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