Proof of concept that FGFR2b can be used to isolate lung stem cells and that FGFR2b signaling is important for lung stem cell activation and therefore epithelial regeneration, tumor development as well as mucous cell hyperplasia.
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The peptide can be made synthetically, produced in high quantities at GMP quality, and lyophilized without a loss in activity. It is inexpensive and naturally biodegradable. The peptide can be genetically engineered to DC targeting molecules like DEC-205, which promotes strong immune responses w.....
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None
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Through use of the present invention, ineffective treatment regimens can be avoided in certain sub-populations of patients suffering from neoplastic diseases, effective treatment regimens can be instituted for patients who were previously refractive to certain treatments, and an overall improvem.....
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In the emergency room situation, mean arterial blood pressure and measures of acidosis are currently used to quantify perfusion in patients requiring resuscitation from shock. Unfortunately, these measures do not provide for early diagnosis or real time responses to therapy. The inventor has demonst.....
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