In broad terms, the PCSD1 model is more representative and predictive of the bone metastatic prostate cancer tumors found in patients. Specifically: Current prostate cancer cell line (SCID mouse) xenograft models, include: - PC3, which produces purely osteolytic lesions in intra-tibial xeno.....
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Unprecedented rapidity Infection can be detected as early as 17 hours post-infection, compared to 72 hours for current methods Viral tropism can be determined in 2-4 days, compared to 3-4 weeks for current methods Extremely sensitive, with as little as 0.0625 MOI required Infection can be traced.....
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These features should prove extremely relevant for clinical applications, from cancer to ophthalmology, where increased efficacy and reduce drug toxicity can enhance the therapeutic profile and/or extend patient life for promising and useful drugs.
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University researchers have developed a nanotechnology for innovative new drug delivery capability, i.e., new nanotechnology-based, magnetically or ultrasonically switchable drug delivery vehicles with easy, remotely on-off switchable release capability. Three types of embodiments of the actuate-abl.....
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Agents that enhance the expression of this miRNA may allow the treatment of diseases with excessive neovascularization and agents that inhibit this miRNA expression may be used to treat diseases with insufficient neovascularization.The specific mode of action is particularly well-suited for combinat.....
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