The Present Inventors Have Discovered That 5-Aminolevulinate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of 5-Aminolevulinate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, 5-Aminolevulinate Synthase Can Be Used As A T.....
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The Present Inventors Have Discovered That Homocitrate Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Homocitrate Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Homocitrate Synthase Can Be Used As A Target For The Iden.....
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The attractiveness of this combinations is their propensity to suppress the expression and function of proteins involved in inflammatory and neuropathic pain and in the same time to activate the antinociceptive mu opiod system involved in pain relief. Targeting the different system, pro-nociceptive.....
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antibody or protein therapy effective at the cellular leveldecreased possibility of side effects due to high selectivity and identification of a specific targetsuitable for treating a number of respiratory conditions, including asthma, steroid-resistant asthma and COPD
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Neutrophil elastase (NE) is a protease secreted by neutrophils during inflammation. Aberrant expression of NE such as in chronic respiratory inflammatory diseases, results in tissue destruction and decline in lung function. Compositions including an NE-targeting agent that targets the pathologic ele.....
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