Lead Inventors: Ioannis Kymissis, Ph. D., Kenneth Shepard, Ph. D., Haig NorianProblem or Unmet Need:Current microfluidic CMOS lab-on-chip systems often struggle with issues of limited durability. Physical damage and electrical shorting are frequent due to the fragile nature of the exposed active are.....
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Gilbert Di Paolo Ph.D.
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Thisinvention describes the use of a responsive hydrogel-based material as acarrier system for in situ deliveryof various bioactive moieties, including small molecules, biomolecules,biomacromolecules (including, but not limited to polysaccharides, glycosaminoglycans,proteins), and cells. The novel c.....
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A mouse transgeinc line overexpressing Prohibitin in the liver and macrophages. This results in the spontaneous development of liver disease and liver cancer.
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BackgroundTraditional methods used to determine theinvolvement of a specific amino acid or group of amino acids to a protein’s structure,stability or function, are alanine scanning or random mutagenesis. However, these approaches are significantlylimited in accessing a residues contribution. With a.....
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