A research tool to study the pH sensing mechanisms of blood vessels and other organs Develop and test therapeutic compounds to modulate blood vessel formation in clinical conditions such as tumor growth, enhance vascular growth in ischemic heart disease, or other diseases with defective pH homeosta.....
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Two-color reporter system to rapidly and efficiently determine hits Small synthetic IRES elements are changeable in length and sequence to accommodate a random mutagenesis approach or a directed design approach Small IRES size (<60 nt) allows for the incorporation of larger (or multiple) genes.....
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Selective stimulation of CAR-transduced T cells but not non-transduced T cellsSelective expansion of CAR-transduced T cellsExpansion of selectively transduced cells to get the same number of transduced cells without expanding non-transduced cellsRapid enrichment of CAR-transduced T cells
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