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First method that requires only picogram quantities of mRNA, while being sensitive to a large dynamic range of measurement concentrations, and thus capable of serving as an attractive method to study clinical samples from patients. Allows targeted amplification with the ability to exclude genes exp..... [更多]
Lead Inventors: Dattananda S. Chelur, Martin Chalfie, Ph.D.Problem or Unmet Need:While proper cellular apoptosis (cell death) is absolutely critical in the prevention of many forms of cancer, control and manipulation of this ubiquitous apoptotic pathway as a developing therapeutic strategy in cancer..... [更多]
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Increased target affinity and specificity compared to peptidesIncreased cellular uptake of EVs (in vivo or in vitro) Directed EVs to particular uptake pathways via targeted receptors (in vivo or in vitro) Biological incorporation of the targeting moiety occurs during EV biogenesis rather than throug..... [更多]
Purdue University researchers have developed a novel strategy using an epidermal growth factor (EGF) targeted toxin, which can be used for elimination of both superficial and invasive bladder tumors. This is a highly efficient, targeted strategy that reduces treatment time from hours (current therap..... [更多]
Internaldetection of system defectsTechniqueprovides for a rapid method to characterize the defect type and structure inthe nanoparticlesOxide-dispersion-strengthened(ODS) metals can be used as ‘tattle-tales’ to determine the ‘state-of-health’for materialsIdealfor extreme environment systemsPreventi..... [更多]
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