There are currently no therapeutics that specifically target toxic protein aggregates following spinal cord and traumatic brain injury.
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Description of Technology Michigan State University’s invention relates to the preparation of pyrrolidines, preferably chiral, from tri-O-acetylketopentulosonic acid methyl esters. In particular, the invention relates to the preparation of 3,4-dihydroxy-5-hydroxymethyl pyrrolidines, which can be sub.....
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Our inventors have derived a novel formulation that fuses elastase resistant peptide PMP-D2 variant to a bioactive protein, a fusion that retains the biological activities of the moieties and will preserve the bioactivity of different growth factors and functional peptide in chronic wounds.
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