Cyclin-dependent protein kinase 5 (Cdk5) has been shown to be involved in neuronal cell differentiation in the form of an active kinase, named neuronal Cdc2-like kinase (Nclk). However, its activity was shown to be suppressed by forming complex with p35nck5a. Therefore, there is a need for identifyi.....
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A novel class of synthetic substances that exhibits DNA cleavage and anticancer activity is discovered. Enediyne is a well-known anticancer agent. Mechanistic study on the new invention confirms that these synthetic substances are converted into enediynes under physiological condition and then deli.....
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High-gain and high-speed amplifiers are vital in analog circuits. Low-voltage design limits the structure of the amplifiers to change from cascode to cascade configuration. In addition, the stability as well as the bandwidth of the cascaded amplifiers are constrained by the existing frequency comp.....
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