The non-invasive detection of fetal chromosomal aneuploidies is demonstrated. Alleles of fetal RNA-SNPs present in a biological sample (e.g. maternal blood) containing fetal RNA are detected and quantified in order to determine the ratio of the alleles. This ratio is compared to a standard control.....
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All current docking methods starting with rigid-body docking do not perform well on protein complexes with significant conformational change during formation and it is urged that new tactics should consider potential conformational changes(s) during complex formation. At present, there are no visua.....
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Silica coated super-paramagnetic iron oxide particles with diameters ranging from 4 to 10 nm with different functionalities on the thin silica layer surface are prepared. These nanoparticles with amine functional peripheries increase intracellular cells (including mesenchymal stem cells) labeling ef.....
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