Methods For Enhancing The Production Of Interferon In Animal Cell Culture Are Described. These Methods Rely On The Manipulation Of The Cellular Levels Of Certain Inducers Of Interferon Production, In Particular Cellular Levels Of Double-Stranded-Rna-Dependent Kinase (Dsrna-Pkr, Or Pkr). In Cell Cult.....
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Methods for enhancing the production of viral vaccines in animal cell culture are described. These methods rely on the manipulation of the cellular levels of certain interferon induced antiviral activities, in particular, cellular levels of double-stranded RNA (dsRNA) dependent kinase (PKR), PKR-def.....
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