Highlights:The World Health Organisation predicts that by 2040, as a result of a growing ageing population, neurodegenerative diseases (NDDs) will have overtaken cancer to become the world’s second leading cause of death, after cardiovascular disease. However, governments and industry have yet to ma.....
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There is a strong need for novel selective and safe approaches for the management of Alzheimer's disease.Development of selective bi-functional small molecules aimed to simultaneously inhibit beta- and gamma secretases in order to reduce amyloid-beta (Aβ) while avoiding toxic effects of full enzymat.....
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Lysosomal Storage diseases (LSD) are inherited genetic defects, resulting in an enzyme deficiency.This deficiency prevents the lysosome from metabolizing cellular waste, and results in their accumulation in the cell. Excessive storage of proteins, saccharides and/or fats can cause permanent cellular.....
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Carbon Nanotubes (CNT) have fascinating properties and have been attracting scientific as well as technological attention in the last few years. Their superb mechanical properties make them desirable as reinforcing fillers in polymeric matrices forming light weight super strong meso-composits. One f.....
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