Highlights:- All epithelial tissues in nature interact with an extracellular matrix. In spite of this, traditional cell culture is carried out on monolayers in plastic and does not take into account the interrelationships of other cells in tissue- These new methods use novel 3D organ-specific matric.....
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A rapidly growing section in the pharmaceutical market is searching for drugs that specifically trigger the cell-death-apoptotic process in cancer cells. We are developing therapies based on smart proteins that restore the ability of cancer cells to commit suicide apoptosis). Particularly, we are us.....
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It is of extreme importance to monitor non-invasively the effect of anti-cancer therapy on tumors. Proliferation of cancer cells causes angiogenesis that increase the perfusion to the tissue. Radiotherapy, chemotherapy or thermotherapy can cause death or damage to the cells and decrease the blood fl.....
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A simple system for diagnosing the state of a cell. The state of a cell can be diagnosed by monitoring the activity patterns of its various pathways. In most cases it is essential to monitor the activity of several genes in order to accurately determine a cell state. Ex vivo techniques allow identif.....
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The Technology:Calcitriol (1,25-dihydroxyvitamin D3), the main hormonally active metabolite of vitamin D was found, in vitro, together with some of its synthetic analogs to have the potential to reduce the damage inflicted to normal tissue by accepted anti-cancer therapy. Calcitriol was found to aff.....
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