UC San Diego researchers are patenting a novel approach to pack nucleic acids into polymeric supramolecular nanostructures and render them resistant to nuclease digestion while maintaining sequence selective hybridization competency. This technology is predicated on the idea that steric hindrance th.....
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Inhibits the HMGCR pathway through a different mechanism than statins. Identifies probes specific to a phenotype of interest and thus does not require prior target identification and validation.
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Researchers at the University of California have discovered a novel tumor suppressor gene, CDK4I, that inhibits the activity of the oncogene CDK4. The CDK4I gene is mutated in the majority of malignant melanomas, gliomas, non-small cell lung cancers, and leukemias. CDK4I is located immediately adjac.....
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A series of novel derivatives of phosphonate compounds has been synthesized. These novel compounds have demonstrated enhanced activity against poxviruses and herpes viruses in tissue culture cells when compared with the unmodified parent molecules. When evaluated against existing alkoxyalkyl analogs.....
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Process can carry out the cell removal in the absence of any chemicals, toxins or enzymes typically used to in order to eliminate the cells.No need for immunosuppressant drugsReduced risk of graph rejectionECM rich in cell signaling components essential for cell adhesion, migration, proliferation an.....
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