Matrix metalloproteinases (MMPs) are a class of zinc-dependent hydrolytic enzymes that function in the degradation and restructuring of extracellular proteins. Overexpression of MMPs has been associated with a variety of diseases, including cancer, arthritis, and cardiovascular disease. Commercializ.....
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BENEFITS OF TARGETING DRUG RESISTANT CARCINOMA CELLS WITH IMMUNOTOXINSΓÇó Immunotoxins have the ability to kill drug resistant carcinomas by an alternative mechanismΓÇó Immunotoxins take advantage of cytokine receptors present on the carcinoma cell surfaceΓÇó Higher specificity of immunotoxins can b.....
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The advantages of this new form of CD40L are: Versatile - treatment for cancer and infectious disease agents such as HIV and Mycobacterium tuberculosis; vaccines; expanding immune cells; and diagnostic tests of immune function; may have utility in neutralizing autoimmune response in diseases su.....
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Using an algorithm, the markedly improved risk prediction can be determined. Also, the invention describes a novel high-throughput assay to measure Lp-PLA2 on isolated Lp(a) particles or isolated apoB particles. Currently, the technique to detect Lp-PLA2 is done in plasma. This invention proposes to.....
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EPLIN-based molecular reagents will prove useful because there are a limited number of biomarkers with proven utility for detection of breast and prostate cancer. EPLIN-based biomarkers can be used in conjunction with or independently of existing biomarkers to facilitate the diagnosis and prognosis .....
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