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CA9 SNP pre-screening of patients with RCC prior to IL-2 intervention helps decrease the incidence of unwarranted treatment and the associated adverse side-effects for low-responders Integration of this SNP into various assays by pharmaceutical companies during clinical trials allows for the identi..... [更多]
In the emergency room situation, mean arterial blood pressure and measures of acidosis are currently used to quantify perfusion in patients requiring resuscitation from shock. Unfortunately, these measures do not provide for early diagnosis or real time responses to therapy. The inventor has demonst..... [更多]
In-vivo stability allows for prolonged integrity in systemic circulation. Micellar structure allows delivery of a broad array of payloads, including, magnetic particles, quantum dots, or a therapeutic agent. Reduced cytotoxicity of both hydrophobic drugs and nanoparticle itself. ..... [更多]
Enhanced targeting of the cell type of interest Non-viral approach Potential to take any drug carrier particle and modify with multivalent ligands Modified drug carriers are more sensitive to receptors on the targeted cell surface [更多]
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