The invention relates to prodrugs of 8-ss-substituted estratrienes of general formula (I) in which the Z group is bonded to the steroid, method for production thereof, pharmaceutical compositions comprising said compounds and use thereof. Said compounds of general formula (I) do not bind to a- and/o.....
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Programmed cell death is a very important cellular process that is critically involved in many diseases. A key step in the programmed cell death is the activation of a series of intracellular proteases, such as caspase-3. The invention is a novel method of detecting the early stage of programmed cel.....
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The present invention introduces a novel process of preparing branched polymers and branched organic materials containing triaroylbenzene moieties as one structural unit by cyclotrimerization. Among conventional methods for synthesis of hyperbranched polymers, it is found that degree of branching is.....
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Bacillus subtilis has been widely used for extracellular production of native and homologous proteins. Based on the use of a synthetic expression/secretion cassette, a new bacterial expression system is developed and may be applied to produce heterologous proteins efficiently as secreted products. .....
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Derivatives of novel carbon bridged cyclopentadienyl-dicarbollide complexes of titanium, zirconium and hafnium display a very high activity as ethylene polymerization catalysts in the absence of a cocatalyst. This invention relates to novel group 4 metallocene catalysts bearing linked cyclopentadien.....
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