The present invention provides the use of analogues and derivatives of dinucleoside polyphosphates with formula (I) or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in one or more of: the treatment of ischemia, inducing ischemic tolerance, modulating cerebral.....
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There is over 10 million new cases of cancer every year. To fight this global health challenges, new treatment approaches, besides traditional strategies like chemotherapy and radiotherapy, are urged. Gene therapy is one of the promising approaches, but a safe and efficient delivery method to tumor .....
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High Throughput And Virtual Screening Methods Are Disclosed That Can Identify Potential Anti-Viral Agents. The Virtual Screening Methods Identify Agents That Interact With A Viral Nucleoprotein Binding Site. The High Throughput Methods Identify Compounds That Inhibit Viral Infection By Binding To Vi.....
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Metal chelates are useful for improving the contrast of X-ray, ultrasound, radionuclide and magnetic resonance (MR) images. However, the metal complexes must be stable and inert so that toxicity resulting from dissociation in the body can be minimized. This invention provides 16-member ring metal ch.....
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The retina is a thin sheet of light sensitive nerve tissue lining the inside of the eye which functions like the film of camera. Retinal detachment (RD) happens when the retina separates from the back wall of the eye and is usually caused by break in the retina. RD is one of the major human eye di.....
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