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BAFF has been reported to be a potent regulator of normal B cell development and function and plays an important role in the resistance to apoptosis of malignant B cells, such as CLL, lymphoma, and myeloma cells. APRIL stimulates tumor cell growth as well as proliferation of primary lymphocytes ..... [更多]
Potentially enhances T cell response in a wider group of cancer patients Improves the understanding of the role of CTLA-4 in auto immune disease and opens up new approaches to treating diseases such as diabetes [更多]
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The new vaccine and strategy are more potent than currently commercially available vaccines in protecting against pulmonary tuberculosis. The bacteria-based booster vaccine invention provides more potent protection against TB infection than protein in adjuvant vaccinations or adenovirus-based ..... [更多]
Potential advantages from molecular engineering linear dual-response mechanisms in the backbone of polymeric nanoparticles include enhanced stability and prolonged shelf life, while also increasing the response sensitivity and efficacy of targeted delivery to diseased environments. In addition, ..... [更多]
This discovery provides for drug discovery and design protocols for isoform drugs that target NOS isoforms and reduce NO production. [更多]
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