The "ciliopathies" are a newly emerging group of diseases due to defects in the function or structure of cellular primary cilia, which are small cellular appendages previously of unknown function. UC San Diego researchers and colleagues have identified five genes for Joubert Syndrome (JS), which is .....
[更多]
Previous work has tried to change only a few pathway enzymes at a time. This more systematic approach can better optimize flux in the pathway.This invention puts all of the genes on together, simplifying the regulation and synthesis of new strains.The constructed modules ca be transferred to other s.....
[更多]
This new cross-linker allows for the MS analysis of multi-subunit protein complexes. In addition, the accompanying software package allows for the fast and accurate identification of DSSO-cross-linked peptides via MS.
[更多]
This novel technology provides unprecedented abilities to evaluate mechanisms of lung disease, injury, response to treatment and repair, and to screen populations of patients at risk of developing lung disease, and to monitor response to treatment in those already afflicted.
[更多]
Advantages and Improvement Over the Art: The present invention provides instantaneous, non-invasive, reversible induction or repression of target genes that can be simply and precisely controlled in a temporal and/or spatial fashion. The system is potentially applicable to any host cell or organism.....
[更多]
| |< <- | [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [121] | -> >| |
