Scientists at UC San Diego have developed a method to identify drug targets using a systems biology approach. Given a network that regulates a disease, the method can predict the effects of inhibiting a set of genes on the marker genes of the disease. For example, if two marker genes are up-regulate.....
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This assay can identify potential drug candidates to treat B-cell-dependent autoimmune diseases, such as lupus and lymphomas. It is ideally suited for high-throughput screening, thereby making it an essential tool for drug discovery and research.
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Bioengineers from UC San Diego have developed a hydrogel-based mineralization process to synthesize porous mineralized bone mimetic material. By varying pendant side-chain lengths to control matrix hydrophobicity, the inventors developed a means to regulate the nucleation of aptatite-like phases on .....
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Easy to designOperate on entire operonsHighly amenable to development and modificationOffer a broader dynamic range for expression of the regulated nucleic acid of interest than with cis-regulators of translation aloneAllow for precise regulation of the level of expression of the nucleic acid of int.....
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Researchers at the University of North Dakota have developed a training device designed for allied health professionals to practice orthopedic tests on a knee or elbow. The devices are anatomically correct, articulable models of the human knee and elbow that allow the major ligaments to be indepen.....
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