For a drug to eliminate HIV-infected cells, a major challenge is to achieve high specificity toward target cells but low cytotoxicity toward normal cells. Maize ribosome-inactivating protein (RIP) contains a 25-amino acid internal inactivation region. Removal of this region generates the active cy.....
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In this application, we propose strategies for using a so-called Rewiring technique for the following VLSI Electronic Design Automation (EDA or CAD) operations: FPGA Technology Mapping and Routing, and Sequential Circuit Retiming. Rewiring is a logic perturbation technique that replaces a signal wir.....
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There is over 10 million new cases of cancer every year. To fight this global health challenges, new treatment approaches, besides traditional strategies like chemotherapy and radiotherapy, are urged. Gene therapy is one of the promising approaches, but a safe and efficient delivery method to tumor .....
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