It has been discovered that As.sub.2O.sub.3 suppresses tyrosine kinase receptors, in particular EGFR and IL-6R, by targeting RTKs to lysosomes and/or proteasome for degradation. This is the basis for the discovery that cancers dependent on RTKs for signaling, proliferation, survival, metastasis and .....
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The present invention provides compositions comprising multi-, toti- or pluripotent cells and peptides forming a self-assembling peptide nanofiber scaffold that reduces or stops proliferation or differentiation of the cells. The present invention also provides methods for inhibiting cell differentia.....
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The Present Invention Relates To An Apparatus And A Method For Wireless Purchase Of Merchandise From A Vending Machine By Using A Cellular Mobile Phone. The Present Invention Permits A Cellular Mobile Phone User To Dial A Sequence Of Code On The Phone To Invoke The Vending Machine To Dispense Mercha.....
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A novel class of saturated or conjugated dendrimers containing at least one strong .sigma.-donating group coordinated to cyclometalated tridentate gold(III) compounds having the chemical structure depicted by generic formula: ##STR00001## wherein: (a) [Au] is a cyclometalated tridentate gold(III) gr.....
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This invention provides a class of organometallic complexes comprising a tridentate isoquinoline-pyridine-benzene based ligand, a mono-dentate ligand and a platinum (II) center which show high emission quantum efficiency and good thermal stability. This invention also discloses organometallic comple.....
[Detail]
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