The invention provides compositions comprising fragments of human telomerase reverse transcriptase (hTERT) which can lead to telomere dysfunction in a cell and reduction of growth and tumorigenicity in cancer cells. The invention also relates to uses of the fragments in the treatment of cancer and i.....
[Detail]
High Throughput And Virtual Screening Methods Are Disclosed That Can Identify Potential Anti-Viral Agents. The Virtual Screening Methods Identify Agents That Interact With A Viral Nucleoprotein Binding Site. The High Throughput Methods Identify Compounds That Inhibit Viral Infection By Binding To Vi.....
[Detail]
Diarylethene-Containing Ligands And Their Coordination Compounds Are Described. The Ligands Display Photochromism With Uv Excitation, While The Coordination Compounds Display Photochromism With Both Excitation In The Uv Region And Excitation Into Lower Energy Absorption Bands Characteristic Of The C.....
[Detail]
Methods And Compositions For Identifying And Treating Obesity And Obesity-Induced Metabolic Disorders Are Provided. One Aspect Provides A Method For The Evaluation Of Risk And Progression Of Glucose Tolerance, Insulin Resistance And Type 2 Diabetes In Mammalian Subjects. The Method Includes Measurin.....
[Detail]
A sequence online analytical processing (S-OLAP) system 50 for analysing an event database (41) storing events (12), the system (50) comprising: an S-OLAP engine (53) to compute an S-cuboid (49) for a query on the event database (41); a sequence query engine (54) to form part of the S-cuboid (49) by.....
[Detail]
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