This invention provides a method for treating or preventing human atrial arrhythmia (fibrillation) using the leading flavone compound acacetin, and its derivatives and analogues that inhibit the ultra-rapidly-activating delayed rectifier potassium current (IKur or IKsus), transient outward potassium.....
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The Present Invention Relates To Novel Oligonucleotide Chimera Used As Therapeutic Agents To Selectively Prevent Gene Transcription And Expression In A Sequence-Specific Manner. In Particular, This Invention Is Directed To The Selective Inhibition Of Protein Biosynthesis Via Antisense Strategy Using.....
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PCT No. PCT/CA91/00009 Sec. 371 Date Jul. 13, 1992 Sec. 102(e) Date Jul. 13, 1992 PCT Filed Jan. 11, 1991 PCT Pub. No. WO91/10734 PCT Pub. Date Jul. 25, 1991The identification, isolation and cloning of DNA sequences coding for mutant forms of the cystic fibrosis gene and their gene product are descr.....
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113 The cystic fibrosis gene and its gene product are described for the 507 mutant form. The genetic and protein information is used in developing DNA diagnosis, protein diagnosis, carrier and patient screening, cloning of the gene and manufacture of the protein, and development of cystic fibrosis a.....
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